MRSCloud currently does not support MEGA-sLASER with the CMRR pulses or timings. I’m currently trying to figure out how to get this sequence in there based on @wclarke’s excellent detective work, but I’m still not sure I’ve fully gotten it right, and Will’s repo does not include the editing pulse used at 3T.
For now, until we have figured out how to accurately simulate this, I would really recommend reaching out to the CMRR folks for LCModel basis sets for this particular setup.
As to the macromolecules, they will not be included in the LCModel basis sets created by MRSCloud anyway. You will need to parametrize those in the LCModel control file. We have previously done some work to figure out a good parametrization. The way we tell LCModel to use it is in osprey/fit/code/osp_fitInitialise.m at develop · schorschinho/osprey, lines 554 and following:
nsimul = 2
chsimu(1) = 'MM09 @ 0.915 +- .02 FWHM= .085 < .1 +- .35 AMP= 3.'
chsimu(2) = 'MM30 @ 3.0 +- .02 FWHM= .085 < 0.12 +- .35 AMP= 2.'
chrato(1) = 'MM30/MM09 = 0.66 +- .2''
ppmgap(1,1) = 1.95
ppmgap(2,1) = 1.2