Date : 2022-07-08 08:58 FID : SPEC_E/fsl_mrs_proc/acc_metab.nii.gz Basis : basis_with_default_mm H2O : None
Fitting of the SVS data was performed using a Linear Combination model as described in [1] and as implemented in FSL-MRS version 2.0.0, part of FSL (FMRIB's Software Library, www.fmrib.ox.ac.uk/fsl). Briefly, basis spectra are fitted to the complex-valued spectrum in the frequency domain. The basis spectra are shifted and broadened with parameters fitted to the data and grouped into 6 metabolite groups. A complex polynomial baseline is also concurrrently fitted (order=2). Model fitting was performed using the truncated Newton algorithm as implemented in Scipy.
[1] Clarke WT, Stagg CJ, Jbabdi S. FSL-MRS: An end-to-end spectroscopy analysis package. Magnetic Resonance in Medicine 2021;85:2950-2964 doi: 10.1002/mrm.28630.