Basis set needed: Philips 3T MEGAPress MMsuppr. GABA80

Dear all,
I’m currently taking baby steps in Osprey, and in order to analyse my own data I would like to ask the community

  1. Is there already a basis set to model MEGApress MM-suppressed data (Philips 3T Achieva, 32ch headcoil, GABA w/ TE=80ms, pulses at 1.5 & 1.9 ppm), and
  2. would you be willing to share it? :slight_smile:

I’m not familiar to basis set modelling at all, and having read the related posts it seems far from trivial…

Thank you very much for your help.


Hi @Stefanie,

Which sequence do you use? The universal sequence from JHU?

I could share a MM suppressed basis set for the universal sequence and I could also help with possible issues during the data analysis.


Hi @Helge,
thank you soooo much! Yes, we use JHU sequences only.

By now, I made my way through the included Osprey example data, and all I need to fix is one minor bug during coregistration (I guess it may be search path related, or likewise… so no worries).
In the meantime, I took a look at Jamie Near’s FID-A toolbox which is also very well documented, but it left me puzzled which simulation tool to adapt for an MM-suppressed MEGA-PRESS - so your response really made my day :slight_smile:

Last december’s online GABA workshop was very helpful and inspiring, and so is the whole MRS community! Loads of thanks to all of you :slight_smile: :smiley:


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No worries!

I’ve just added the basis set into the latest develop branch on GitHub. For the jobFile definition I’d set the co-edited MM model to none:              = 'none';              = 14;   

Great to hear that the EDITINGSCHOOL was helpful. And I’m also very excited to see this forum thrive! :smiley:


Hi both,

Be mindful that the JHU patch allows two pulse sets (the default Philips pulses, and then what @Helge referred to as ‘universal’, which are custom pulses that @richardedden cooked up and that we have ported across vendors). Just make sure you’re using the correct basis set that corresponds to the pulse set you’ve used during acquisition.