Dear Developers,
I am a beginner in MRS signal processing. We have a 3T GE scanner that we use for scientific projects besides everyday clinical work. I use Osprey for quantification of the general MRS applications (PROBE-p TE=35 and 144). It works perfectly.
I am very much interested in 2HG quantification, and I set up a sLaser sequence with 110 TE for this project. I tried to simulate the basis sets using two different approaches:
- I used the MATLAB code BasisSetSimulation by Jessica Archibald. In this case, I received basis sets shifted by about -2ppm. I assume that the problem would be the center frequency; however, it is set to 2.02, which is the correct value in my case (if I am not mistaken…). Do you have any idea what could be the problem?
- In parallel, I also tried MRSCloud. Unfortunately, I could not figure out how to transform the .RAW format to .mat. Is there any way to do it? In other basis set simulators, I had to be very specific with the measurement parameters, but not with MRSCloud. What is the reason for this? It didn’t even ask for the B0 field strength. Do I complete the “missing” data while applying the .RAW format?
Which one is the better, more reliable method? Do you have any further suggestions how I can progress?
Best,
András