Basis sets for 3T MEGA-PRESS GABA Editing TE: 135

Analysis / Modeling
1

Hi everyone,

I need basis files for my Siemens 3T MEGA-PRESS GABA-editing data with TE = 135 ms. I generated a basis set on MRSCloud, but it didn’t work due to a “wrong field strength” error on LCModel.

I also found similar basis files, but they were created for TE = 68 ms.
Is there any way to convert those to TE = 135 ms ?

I would really appreciate any help. Thank you!

2

B0 is indicated as 2.89T in the .basis files. Would that be the problem?
You cannot directly convert basis sets from 68 to 135 ms.

3

i couldn’t find such an entry in the basis file. Although mrscloud basis sets worked fine for my other data.

4

Technical questions aside, I have a question about the protocol - what signal are you intending to edit?

The 3 ppm GABA signal is fully inverted at TE = 68 ms, and will therefore be in-phase again at TE = 135 ms - I’m not sure you’ll see anything?!

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5

@ardacanbas1, try to load the .basis files with io_readlcmraw_basis.m from FID-A (GitHub - CIC-methods/FID-A: Toolbox for simulation and processing of in-vivo magnetic resonance spectroscopy (MRS) data) in MATLAB. You will find B0 in each one of the basis function and you can change them from 2.89 to 3.0.

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6

Good question :grin:

I think the TE = 135 ms data was some kind of test. I checked again, and most of my data actually has TE = 68 ms. Also, my basis set is working perfectly fine now!

Thanks.

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