Combined fMRI-fMRS for Siemens 7T Terra (VE11U) or 3Ts with VE scanners

uzayemir · February 23, 2023, 12:00am

Dear All,

Finally, we have implemented the Combined fMRI-fMRS sequence (1,2) for the Terra (VE11U) and 3Ts with VE scanners. This was a collaborative effort with David Norris, Andre Vanderkouwe, and Zoe Kourtzi’s groups. Particularly, Shahrokh Abbasi Rad put enormous effort and made it feasible. If you want to use this sequence, please email Shah (SABBASI-RAD at mgh.harvard.edu) for details and C2P paperwork.

Uzay

Koolschijn RS, Shpektor A, Clarke WT, Ip IB, Dupret D, Emir UE, Barron HC. Memory recall involves a transient break in excitatory-inhibitory balance. Elife.2021 Oct 8;10. doi: 10.7554/eLife.70071. PubMed PMID: 34622779; PubMed Central PMCID: PMC8516417.
Ip IB, Berrington A, Hess AT, Parker AJ, Emir UE, Bridge H. Combined fMRI-MRS acquires simultaneous glutamate and BOLD-fMRI signals in the human brain. Neuroimage. 2017 Jul 15;155:113-119. doi: 10.1016/j.neuroimage.2017.04.030. Epub 2017 Apr 19. PubMed PMID: 28433623; PubMed Central PMCID: PMC5519502.

uzayemir · April 2, 2023, 9:29pm

Here are some results from the VE implementation of the sequence.

Thanks to Cecilia Steinwurzel for performing analysis and acquisition.

3D EPI

MRS acquisitions

15mm3 isotropic

20 mm3 isotropic

uzayemir · July 13, 2023, 10:37am

combined fMRI (1 mm 3 resolution) and fmrs (8 mm3)