This is interesting. I assume that this is the CMRR implementation of sLASER for GE. I am working with data I received from another collaborator using this sequence. For them, the water-referenced results are also totally off (Metabolite value estimates seem really low? - #2 by Helge) but are extremely low. I have, up to now, not managed to get a handle on that, but maybe your data could give me some new insight into where this is going wrong.
Would you be able to share the data with us?
Helge