Hi everyone,
I hope this question isn’t too basic, but I would really appreciate your input on a detail regarding the relative CRLB% in Osprey LCModel fitting.
I understand that using relative CRLB for data screening may introduce bias, but it’s still useful for assessing spectrum quality. My specific question is about calculating the relative CRLB for GABA+ in the difference spectrum.
Should I use the absolute CRLB from the diff_CRLB.tsv file, divided by the metabolite amplitude from diff1_amplMets.tsv, and then multiply by 100% to get the relative CRLB for GABA+?
Thanks in advance for your time and help—I really appreciate it!