I’m wondering about the role of the option coMM3 in Osprey. I guess that it has to do with how the fitting procedure treats coediting of some macromolecule, possibly MM20, which has a peak at 3.00 ppm?
I’m currently collecting data both with the standard GABA editing sequence, with editing pulses at 1.9 ppm (ON) and 7.46 ppm (OFF), and with the MM supressed variant, with editing pulses at 1.9 ppm (ON) and 1.5 ppm (OFF).
Should coMM be set different for these two sequences and what should it be set to? Is there any other considerations for these two types of editing?
On a completely different thing, and perhaps meriting a separate topic, do you have any plans for support of functional MRS, in the sense that data can be collected during a set of conditions (“task”/“rest” blocks), such that one can separate the data for “task” and “rest” in the analysis. For example, the experiments has been set up so that subspectrum [(n-1)16+1 : n16] corresponds to “task” for even n and to “rest” for odd n. (The blocks of 16 subspectra would be 8 OFF and 8 ON, respectively, and n would typically go up to 32 or more.) It is certainly possible to sort the data after loading and modification of the MRSCont structure but it would be awesome to have it built into Osprey from start.