Water reference loop for MEGA-PRESS

Data Acquisition Edited 1H-MRS
1

Dear MRSHub experts,

I recently started programming MEGA-PRESS sequence on GE Discovery MR750 3T, wondering how I should set dummy loop and water reference loop. The structure of the sequence is dummy loop - spectra loop(ON/OFF alternating) - reference loop.

Should they be one of the following scenarios?

  1. no editing pulses (just plain PRESS with TE=68ms)
  2. same as EDIT-ON loop
  3. same as EDIT-OFF loop

Thanks for your kindly help in advance!
Nan