Water Reference Set-up HERMES HERCULES

Data Acquisition Edited 1H-MRS
1

Dear MRSHub Mindhive,

I have installed and set up the HERMES and HERCULES sequences based on the Siemens VE11A–C, E, P installation guide from June 2020. As for setting up water reference scans for i. HERMES: GABA&GSH editing and ii. HERCULES, attached is a quick breakdown of the parameters I selected for each water ref. I am hoping someone on here may be able to let me know if these changes are correct, or what may need amending. Please let me know if I can help provide any further information.

WaterRef_SetUp_HercHerm
WaterRef_SetUp_HercHerm2951×1650 295 KB

Lastly, for a new study I am setting up, we are interested in quantifying: NAA, Ins, GABA+, Glx, GSH. Given that, would you anticipate that HERCULES and HERMES (GABA and GSH) would perform similarly for these metabs? If not, which sequence would you recommend?

Thank you for your help; it is greatly appreciated.

All the best,
Jacob

2

Hi @JacobMLevenstein,

The HERMES settings look correct.

For HERCULES, set Edit Pulse Frequency 1 to 7.5 ppm, Edit Pulse Frequency to 8 ppm, and Edit Off Frequency to 10 ppm.

Best,
Helge

3

Hello @Helge,

Thank you for the quick response and for the information!

Very much appreciated,
Jacob